Is Eliquis hard on the kidneys?

Asked by: Prof. Alec Ziemann  |  Last update: January 23, 2024
Score: 4.5/5 (67 votes)

Herein, we report clinical history and kidney biopsy findings in a patient on apixaban (Eliquis). Initiation of treatment with apixaban resulted in aggravation of preexisting mild acute kidney injury (AKI).

Which blood thinner is safest for kidney disease?

Unfractionated heparin (UFH) is preferred because it has a short half‐life that allows for the anticoagulant effect to wear off within 1 to 4 hours, even in patients with severe renal dysfunction at high hemorrhagic risk.

Can blood thinners affect your kidneys?

Among patients who take blood thinner there is a high prevalence of reduced kidney function, ranging from mild to severe. "Although warfarin is very effective in protecting against blood clots it can also cause serious bleeding complications," commented lead author Nita A.

Is Eliquis easier on kidneys than Xarelto?

Only 25 percent of Eliquis is eliminated by the kidneys - and the rest by the liver - which some doctors say could make it more appropriate than Pradaxa or Xarelto for older patients and those with kidney problems.

What is the downside of taking Eliquis?

Common Eliquis side effects include nosebleeds, bleeding gums, bruising easily and bleeding that takes longer to stop. Internal bleeding is a rare serious side effect. Stopping Eliquis suddenly may increase the risk of blood clots.

Unbelievable: These 5 Medications Could Be Ruining Your Kidneys Without You Knowing!

21 related questions found

How long should you stay on Eliquis?

How long will I be on ELIQUIS? Your doctor will decide the duration of your treatment. After at least 6 months of treatment for DVT/PE, your doctor may ask you to continue on a lower dose of ELIQUIS to help reduce the risk of them happening again.

Which blood thinner is easiest on kidneys?

DOACs are a novel type of blood thinner that require less monitoring and are easier to take than VKAs like warfarin. They've been shown to work as well – if not better – at preventing strokes with fewer side effects. DOACs also appear safer than VKAs in patients with early stage kidney disease.

What blood thinner is an alternative to Eliquis?

There are also several newer blood thinners available now, including Eliquis® (apixaban), Pradaxa® (dabigatran), Xarelto® (rivaroxaban), and Savaysa® (edoxaban). For people who need an alternative, there are heart procedures that can effectively reduce the risk of stroke.

What medications can damage your kidneys?

Nonsteroidal anti-inflammatory drugs (NSAIDs), diuretics, and angiotensin-converting enzyme (ACE) inhibitors have all been linked to kidney problems. Certain medications given in hospital settings, such as iodinated radiocontrast, vancomycin, and aminoglycoside antibiotics, can also hurt the kidneys.

What are the signs of kidney effects?

Signs and symptoms of acute kidney failure may include:
  • Decreased urine output, although occasionally urine output remains normal.
  • Fluid retention, causing swelling in your legs, ankles or feet.
  • Shortness of breath.
  • Fatigue.
  • Confusion.
  • Nausea.
  • Weakness.
  • Irregular heartbeat.

How to improve kidney function?

6 Things People with Kidney Disease Should Do:
  1. Lower high blood pressure.
  2. Manage blood sugar levels.
  3. Reduce salt intake.
  4. Avoid NSAIDs, a type of painkiller.
  5. Moderate protein consumption.
  6. Get an annual flu shot.

How do you know if your kidneys are damaging?

Protein in the urine is an early sign that the kidneys' filters have been damaged, allowing protein to leak into the urine. This puffiness around your eyes can be due to the fact that your kidneys are leaking a large amount of protein in the urine, rather than keeping it in the body. Your ankles and feet are swollen.

Which drug is high toxic to kidney?

Antimicrobials such as aminoglycosides, antifungals (amphotericin B), beta-lactams (cephalosporins, penicillins), quinolones (ciprofloxacin), rifampin (Rifadin), and vancomycin (Vancocin) can lead to drug-induced acute renal failure.

What is the best blood thinner with the least side effects?

Direct oral anticoagulants, or DOACs, have been found to be safer than warfarin for patients with atrial fibrillation. A new study published in November 2022 in Annals of Internal Medicine found apibaxan to be the safest blood thinner among DOACs, including dabigatran, edoxaban and rivaroxaban.

Can AFIB cause kidney damage?

Third, AF can lead to a decrease in left ventricular contractility and cardiac output. Therefore, renal perfusion is reduced, resulting in activating the renin-angiotensin-aldosterone system, which further impairs kidney function and accelerated progression to ESRD [7].

Which blood thinner is safer Eliquis or Xarelto?

Are there any differences in side effects between Eliquis Vs Xarelto? Two large retrospective studies (78,702 patients [Study 1] + 581,451 patients [study 2]) have found that overall, Eliquis appears to be safer than Xarelto.

What is the natural version of Eliquis?

Vitamin E

Vitamin E is a natural blood thinner because of its anticoagulant effects. Studies support that vitamin E has anti-clotting activity and works as a potent blood thinner. Supplementing with vitamin E and consuming vitamin E foods can help prevent diseases of the heart and blood vessels.

Is Eliquis the only blood thinner for AFib?

But a newer group of medications called direct oral anticoagulants (DOACs) are now considered the best blood thinners for AFib treatment. DOACs include Pradaxa, Xarelto, and Eliquis.

What foods help repair kidneys?

10 Superfoods for People with Kidney Disease
  • Red Peppers. Also low in potassium but high in flavor. ...
  • Cauliflower. High in vitamin C, folate and fiber, cauliflower helps your body fight off toxins. ...
  • Blueberries. ...
  • Egg Whites. ...
  • Garlic. ...
  • Fish. ...
  • Red Grapes. ...
  • Olive Oil.

What blood type is prone to kidney disease?

Our finding shows that blood group B individuals are more susceptible and suffer severely in renal disease than other blood group individuals. We also discovered that D-galactose is responsible for the severity of acute renal failure.

What vitamins can be hard on the kidneys?

You may need to avoid some vitamins and minerals if you have kidney disease. Some of these include vitamins A, E and K. These vitamins are more likely to build up in your body and can cause harm if you have too much. Over time, they can cause dizziness, nausea, and even death.

Is 5mg of Eliquis a lot?

The typical Eliquis dosage for adults with atrial fibrillation — specifically nonvalvular atrial fibrillation — is 5 mg by mouth twice daily. But you may receive 2.5 mg in certain situations, depending on your age, body weight, and kidney health.

Do people ever stop taking Eliquis?

Your doctor will decide how long you should take ELIQUIS. Don't change your dose or stop taking ELIQUIS without first talking with your doctor. Stopping ELIQUIS increases your risk of having a stroke if you are taking ELIQUIS for atrial fibrillation not caused by a heart valve problem.

Is fatigue a side effect of Eliquis?

However, tiredness can be a symptom of blood loss or anemia, which are possible side effects of Eliquis. If you have tiredness while taking Eliquis, talk with your doctor. They may check you for any symptoms of internal bleeding.