Is it possible to keep weight off after Ozempic?
Asked by: Wilson Mante | Last update: November 12, 2025Score: 4.1/5 (29 votes)
What percentage of people gain weight back after Ozempic?
On average, the group that took Ozempic lost 17.3% of their body weight between weeks 0 and 68, while the placebo group lost 2%. After stopping Ozempic use, the Ozempic group regained an average of 11.6% body weight, while the placebo group regained 1.9%.
Can you maintain weight loss after semaglutide?
At the end of the study, 21 out of 25 subjects had lower body weight compared to baseline. Nine of these subjects continued to lose weight after stopping semaglutide. In 6 subjects, body weight remained stable after discontinuation of semaglutide.
Do you lose weight after you stop taking Ozempic?
But many people also experience weight loss while taking it. When you stop taking Ozempic, you may notice some immediate effects, like an increase in appetite or blood sugar levels. Most people will gain back most of the weight that they lost while taking Ozempic.
Is Ozempic weight loss permanent?
What happens when you stop taking Ozempic or Wegovy? Weight loss from Ozempic or Wegovy isn't permanent. If you stop taking these medications, you will start to gain weight over time.
I’m worried I’ll gain weight when I get off Ozempic. Any tips?
Do you ever stop losing weight on Ozempic?
Drugs such as Ozempic and Wegovy eventually reach a weight loss plateau, beyond which further weight loss slows or stops. Like any other healthy weight loss method, the body eventually settles at an appropriate weight, which may or may not correspond with that person's weight loss goals.
Do you have to be on semaglutide forever weight loss?
No, you don't have to take semaglutide for weight loss forever. You can stop if the side effects are unmanageable or when you reach your weight loss goal. But always let your healthcare provider know before you stop taking semaglutide (or any other medication).
How did Kelly Clarkson lose weight?
Kelly Clarkson's weight loss was motivated by health concerns, including autoimmune and thyroid conditions. She combined diet changes, such as adopting a lectin-free diet, with regular exercise like walking. Clarkson's journey included using weight loss medication, although she emphasized a holistic approach.
How do you keep weight off after losing it?
Activity that uses 1,500 to 2,000 calories per week is recommended for maintaining weight loss. Adults should try to get at least 40 minutes of moderate to vigorous level physical activity at least 3 to 4 times per week. Diet and exercise are vital strategies for losing and maintaining weight.
How long do you stay on Ozempic for weight loss?
There's no set amount of weight loss that indicates you're ready to stop using Ozempic®. If you're taking it and it's working, and any side effects you're getting are tolerable, your prescriber will generally recommend that you stay on it.
How do I taper off Ozempic?
Lowering the dose slowly each week under a healthcare provider's supervision can minimize these effects. If you're worried about regaining weight after stopping Ozempic, having a plan to maintain a healthy lifestyle during this transition can help.
How to flush semaglutide out of your system?
How to flush Ozempic out of your system. It's not possible to get Ozempic or Wegovy out of your system faster than between five and seven weeks. If you want to stop taking semaglutide, talk to your healthcare provider first so they can help you safely make the transition and minimize your side effects.
Has anyone kept the weight off after stopping Mounjaro?
Many people lose a significant amount of weight while using Mounjaro, up to 22.5% over 72 weeks on a 15mg maintenance dose. However, when they stop treatment much of their hard work is undone, regaining up to 14% of their lost body weight. Yet, people who continue to use Mounjaro continue losing weight.
How did Adele lose weight?
Adele's routine involved daily workouts, including weight training and cardio. She worked with a trainer to create a balanced plan that fit her lifestyle. This consistent exercise helped her build strength and boost her fitness level.
How did Melissa McCarthy lose weight?
Melissa told People magazine that after she landed her role on Gilmore Girls, she attempted a doctor-supervised all-liquid diet, which led her to lose 70 pounds in four months.
Did Christina Aguilera use Ozempic to lose weight?
She admitted that prior to taking Ozempic, she did attempt to lose the weight naturally through diet and exercise.
How do you keep weight off after Ozempic?
Keep Up With Exercising
Experts typically recommend 150 minutes of moderate-intensity exercise per week, or roughly 30 minutes daily, five days a week. We recommend walking briskly, cycling, swimming, the elliptical, or running to achieve these results. The most intense the activity, the more you'll burn off.
Can I lose 20 pounds in a month with semaglutide?
How fast you can lose 20 lbs on semaglutide (Wegovy) depends on your starting weight and other factors. If you weigh 232 lbs at the start of Wegovy treatment, you can expect to lose 20 lbs in around 16-20 weeks (4-5 months).
Does Ozempic stop working?
For example, clinical studies state that other semaglutide medications effectively reduce the body weight of people with overweight by 15% over 68 weeks. This means that as you stop administering Ozempic, the effects of the medication will also stop.
Does Ozempic lose potency over time?
If you use expired Ozempic, it may not work as well. That's because the active ingredient, semaglutide, can start breaking down and lose potency over time. The manufacturer can only guarantee stability if the pen is used within the expiration (or in-use) date.
How to break Ozempic plateau?
Increase your physical activity
Adding more movement to your daily routine can help you burn additional calories and break through a plateau. Whether incorporating strength training, trying a new fitness class, or simply increasing your daily steps, boosting your activity level can reignite your progress.