Is there a substitute for Prograf?

• Rapamune.
• Mycophenolate mofetil.
• Sirolimus.
• Everolimus.
• Cyclosporine.
• Imuran.

• Prednisone.
• Tacrolimus (Prograf)
• Cyclosporine (Neoral)
• Mycophenolate Mofetil (CellCept)
• Imuran (Azathioprine)
• Rapamune (Rapamycin, Sirolimus)

What happens if you stop taking tacrolimus?

While you are being treated with tacrolimus, and after you stop treatment with it, do not have any immunizations (vaccines) without your doctor's approval. Tacrolimus may lower your body's resistance and the vaccine may not work as well or you might get the infection the vaccine is meant to prevent.

What are the long term side effects of Prograf?

Is tacrolimus hard on your kidneys?

Tacrolimus works by suppressing the immune system to prevent the white blood cells from trying to get rid of the transplanted organ. Tacrolimus is a very strong medicine. It can cause side effects that can be very serious, such as kidney problems.

How long do you take tacrolimus after kidney transplant?

Three-year posttransplant graft survival in renal-transplant patients with graft function at 6 months receiving tacrolimus or cyclosporine microemulsion within a triple-drug regimen. Transplantation 2003; 76:1686. Williams D, Haragsim L. Calcineurin nephrotoxicity.

Why do kidney transplants only last 10 years?

While transplanted organs can last the rest of your life, many don't. Some of the reasons may be beyond your control: low-grade inflammation from the transplant could wear on the organ, or a persisting disease or condition could do to the new organ what it did to the previous one.

Is cyclosporine better than tacrolimus?

Authors' conclusions: Tacrolimus is superior to cyclosporin in improving graft survival and preventing acute rejection after kidney transplantation, but increases post-transplant diabetes, neurological and gastrointestinal side effects.

What drug can be substituted for CellCept?

Mycophenolate mofetil is available now as a generic alternative to Cellcept.

Is there a shortage of tacrolimus?

There is a national shortage of generic tacrolimus which may result in difficulty obtaining the medication. Currently, only generic tacrolimus is affected, brand products and long-acting formulations are not currently affected.

How long is tacrolimus good for?

Tacrolimus ointment is intended to be used for a short period of time (up to six weeks). It should not be used every day over a long period of time.

What is the difference between cyclosporine and tacrolimus?

Tacrolimus and cyclosporine differ in their chemical structure: cyclosporine is a cyclic endecapeptide [8], whereas tacrolimus is a macrocyclic lactone [9]. However, they act in a similar manner. Both are calcineurin inhibitors; their main mechanism of action involves inhibition of this important phosphatase [1].

Is sirolimus the same as tacrolimus?

Prograf (tacrolimus) is a good medicine that prevents rejection of an organ transplant, but you will need to be on it lifelong. Prevents rejection of a transplanted organ. Rapamune (sirolimus) is a reliable medicine that prevents rejection of an organ transplant but requires consistent monitoring.

How can I increase my tacrolimus naturally?

Tacrolimus should be taken on a consistent schedule before or after you eat at the same times each day. Grapefruit and grapefruit juice may increase the amount of tacrolimus in your body.

Do you have to take anti rejection drugs forever?

After an organ transplant, you will need to take immunosuppressant (anti-rejection) drugs. These drugs help prevent your immune system from attacking ("rejecting") the donor organ. Typically, they must be taken for the lifetime of your transplanted organ.

What foods affect tacrolimus levels?

Avoid excessive intake of high potassium foods (bananas, oranges, orange juice, potatoes, spinach, etc). Do not eat grapefruits, grapefruit juice or any soda (Fresca) or fruit juice blend that contains grapefruit juice. Grapefruit can increase your levels of tacrolimus to a potentially toxic level.

Who should not take tacrolimus?

You should not use this medicine if you are allergic to tacrolimus or hydrogenated castor oil, or if you have used cyclosporine (Neoral, Sandimmune, Gengraf) within the past 24 hours. Using tacrolimus may increase your risk of developing serious infections or certain types of cancer, such as lymphoma or skin cancer.

What is a normal tacrolimus level for a kidney transplant patient?

Generally, the tacrolimus trough level maintained between 5.35 and 7.15 ng/mL may be optimal during the first month after living relative kidney transplantation among the Chinese.

How much does Prograf cost without insurance?

The average retail price is $473.75 for 60, 1MG Capsule of Prograf.

Does tacrolimus affect sleep?

Conclusion: In our population, insomnia is common after lung transplantation, with prevalence greater than the general population. Higher cumulative exposure to tacrolimus may contribute to insomnia in this group.

Does Prograf cause memory loss?

In 100 people receiving Tacrolimus, from 4 to 20 may have: Damage to organs (heart, lungs, brain, others) which may cause changes in thinking, confusion, memory loss or shortness of breath. Allergic reaction which may cause rash, low blood pressure, wheezing, shortness of breath, swelling of the face or throat.