What is another name for Prograf?
Asked by: Kadin Carter Sr. | Last update: April 26, 2023Score: 4.6/5 (14 votes)
Tacrolimus (Astagraf XL, Envarsus XR, Prograf) is used along with other medications to prevent rejection (attack of a transplanted organ by the immune system of a person receiving the organ) in people who have received a kidney transplant.
What is the generic name of Prograf?
Introduction. If you've had an organ transplant or if you have eczema, you may want to learn more about tacrolimus (Astagraf XL, Envarsus XR, Prograf, Protopic). Tacrolimus is a generic prescription drug that comes as a liquid for injection, a capsule, and an ointment.
What is the generic name for tacrolimus?
Prograf is the brand name while tacrolimus is the generic name. Tacrolimus is also available as an ointment called Protropic. Tacrolimus is an immunosuppressant. The oral form is used to suppress the immune system in people who have had an organ transplant.
Is Prograf and tacrolimus the same?
Tacrolimus (Prograf ®) is an immunosuppressant drug used to prevent and treat organ rejection in children who have had liver transplants. It is used for long-term immunosuppression.
Is tacrolimus a high risk drug?
Tacrolimus is a very strong medicine. It can cause side effects that can be very serious, such as kidney problems. It may also decrease the body's ability to fight infections. You and your doctor should talk about the benefits of this medicine as well as the risks of using it.
Tacrolimus (Prograf) – Prescription Medication Instructions for Post-Transplant Patients
What are the long term side effects of tacrolimus?
Commonly reported side effects of tacrolimus include: opportunistic infection, diabetes mellitus, infection, headache, hyperglycemia, hyperkalemia, increased blood urea nitrogen, increased serum creatinine, mental status changes, nephrotoxicity, sensation disorder, and tremor.
What are the long term side effects of Prograf?
- problems from medicine errors. ...
- high blood sugar (diabetes). ...
- kidney problems.
- nervous system problems. ...
- high levels of potassium in your blood.
- high blood pressure.
- changes in the electrical activity of your heart (QT prolongation).
- heart problems (myocardial hypertrophy).
When did Prograf go generic?
On August 25, 2017, the FDA approved an AP-rated generic version of Astellas' Prograf (tacrolimus) 5 mg/mL injection. Prograf is approved for the prophylaxis of organ rejection in patients receiving allogeneic kidney, heart, or liver transplants.
Why is there a shortage of tacrolimus?
A: We do not know all of the reasons why tacrolimus is in shortage. One reason is a raw ingredient shortage leading to manufacturer delays in producing tacrolimus. Generic tacrolimus is being allotted to pharmacies based on past usage.
Who should not take tacrolimus?
You should not use this medicine if you are allergic to tacrolimus or hydrogenated castor oil, or if you have used cyclosporine (Neoral, Sandimmune, Gengraf) within the past 24 hours. Using tacrolimus may increase your risk of developing serious infections or certain types of cancer, such as lymphoma or skin cancer.
What can I use instead of tacrolimus?
Nulojix® is an injectable medication that works in a different way than any other anti-rejection medicines available. It was designed as a potential replacement medication for Prograf® (tacrolimus) or Neoral® (Gengraf®, cyclosporine).
Does Medicare pay for tacrolimus?
Do Medicare prescription drug plans cover tacrolimus? Yes. 100% of Medicare prescription drug plans cover this drug.
How much does Prograf cost without insurance?
The cost for Prograf intravenous solution (5 mg/mL) is around $2,398 for a supply of 10 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What is the generic name for CellCept?
CellCept is available in a generic form called mycophenolate mofetil. A generic drug is an exact copy of the active drug in a brand-name medication.
Can tacrolimus cause liver damage?
The liver injury due to tacrolimus is usually mild and self-limiting and responses rapidly to dose adjustment or drug discontinuation. Other calcineurin inhibitors and immunosuppressants are generally tolerated, but rare instances of cross sensitivity to hepatic injury by cyclosporine and tacrolimus have been reported.
Can you switch brands of tacrolimus?
Changing oral tacrolimus products
This updated recommendation does not preclude patients changing to a different tacrolimus brand if the prescriber considers this to be of benefit to the patient.
Does tacrolimus make your hair fall out?
While those medications are essential in allowing the body to accept the transplant, like virtually all medicine, they can have side effects. Tacrolimus can cause hair loss. Ironically, cyclosporine can cause unwanted hair growth in some people but doesn't affect those who are already totally bald.
What happens when your tacrolimus level is low?
The level of tacrolimus in the blood must be maintained within a narrow therapeutic range. If the concentration is too low, organ rejection may occur; if it is too high, then the person may experience symptoms associated with toxicity. Dosages must be tailored to the individual.
Who makes generic tacrolimus?
Currently, five companies manufacturer generic tacrolimus in the U.S. (Accord Healthcare, Dr. Reddy Labs, Panacea Biotec Ltd., Sandoz, and Mylan); Sandoz also makes a branded generic drug (Hecoria).
Is CellCept same as tacrolimus?
Prograf (tacrolimus) is a good medicine that prevents rejection of an organ transplant, but you will need to be on it lifelong. CellCept (mycophenolate) is a first-choice medication for preventing organ rejection since it doesn't hurt the kidneys or liver like its alternatives.
Does tacrolimus affect the heart?
In 100 people receiving Tacrolimus, from 4 to 20 may have: Damage to organs (heart, lungs, brain, others) which may cause changes in thinking, confusion, memory loss or shortness of breath.
Does tacrolimus affect sleep?
Conclusion: In our population, insomnia is common after lung transplantation, with prevalence greater than the general population. Higher cumulative exposure to tacrolimus may contribute to insomnia in this group.
How long can you take tacrolimus?
How long will I have to take tacrolimus? You will likely be on this immunosuppressant or one similar to it for as long as your transplanted organ is functioning. Over time, there may be some changes to the types of immunosuppressants you will take.
What is a normal tacrolimus level after kidney transplant?
Generally, the tacrolimus trough level maintained between 5.35 and 7.15 ng/mL may be optimal during the first month after living relative kidney transplantation among the Chinese.