What is the generic for Prograf?

Asked by: Sandy Mosciski  |  Last update: October 10, 2022
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Introduction. If you've had an organ transplant or if you have eczema, you may want to learn more about tacrolimus (Astagraf XL, Envarsus XR, Prograf, Protopic). Tacrolimus is a generic prescription drug that comes as a liquid for injection, a capsule, and an ointment.

Is there a generic for Prograf?

(Tacrolimus)

Prograf is a prescription medication that is used along with other drugs to prevent the rejection of a liver, heart, or kidney transplant. Tacrolimus is the generic version of this drug.

Is tacrolimus and Prograf the same?

Tacrolimus (Prograf ®) is an immunosuppressant drug used to prevent and treat organ rejection in children who have had liver transplants. It is used for long-term immunosuppression.

Is there a generic for tacrolimus?

Prograf is the brand name while tacrolimus is the generic name. Tacrolimus is also available as an ointment called Protropic. Tacrolimus is an immunosuppressant. The oral form is used to suppress the immune system in people who have had an organ transplant.

What is another name for Prograf?

Tacrolimus (Astagraf XL, Envarsus XR, Prograf) is used along with other medications to prevent rejection (attack of a transplanted organ by the immune system of a person receiving the organ) in people who have received a kidney transplant.

Tacrolimus (Prograf) – Prescription Medication Instructions for Post-Transplant Patients

44 related questions found

How long do you take tacrolimus after kidney transplant?

Three-year posttransplant graft survival in renal-transplant patients with graft function at 6 months receiving tacrolimus or cyclosporine microemulsion within a triple-drug regimen. Transplantation 2003; 76:1686. Williams D, Haragsim L. Calcineurin nephrotoxicity.

Is tacrolimus a high risk drug?

Tacrolimus is a very strong medicine. It can cause side effects that can be very serious, such as kidney problems. It may also decrease the body's ability to fight infections. You and your doctor should talk about the benefits of this medicine as well as the risks of using it.

Does Medicare pay for tacrolimus?

Do Medicare prescription drug plans cover tacrolimus? Yes. 100% of Medicare prescription drug plans cover this drug.

When did Prograf go generic?

On August 25, 2017, the FDA approved an AP-rated generic version of Astellas' Prograf (tacrolimus) 5 mg/mL injection. Prograf is approved for the prophylaxis of organ rejection in patients receiving allogeneic kidney, heart, or liver transplants.

Why is there a shortage of tacrolimus?

A: We do not know all of the reasons why tacrolimus is in shortage. One reason is a raw ingredient shortage leading to manufacturer delays in producing tacrolimus. Generic tacrolimus is being allotted to pharmacies based on past usage.

What are the long term side effects of tacrolimus?

Commonly reported side effects of tacrolimus include: opportunistic infection, diabetes mellitus, infection, headache, hyperglycemia, hyperkalemia, increased blood urea nitrogen, increased serum creatinine, mental status changes, nephrotoxicity, sensation disorder, and tremor.

What are the long term side effects of Prograf?

What Else Should I Know?
  • problems from medicine errors. ...
  • high blood sugar (diabetes). ...
  • kidney problems.
  • nervous system problems. ...
  • high levels of potassium in your blood.
  • high blood pressure.
  • changes in the electrical activity of your heart (QT prolongation).
  • heart problems (myocardial hypertrophy).

How much does Prograf cost without insurance?

The cost for Prograf intravenous solution (5 mg/mL) is around $2,398 for a supply of 10 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

Can you switch brands of tacrolimus?

Changing oral tacrolimus products

This updated recommendation does not preclude patients changing to a different tacrolimus brand if the prescriber considers this to be of benefit to the patient.

Who makes generic tacrolimus?

Sandoz is the #1 provider of generic transplant medications in Europe5 and its predecessor company was the pioneer behind the immunosuppressant cyclosporine discovered in the 1970s by Sandoz scientists6.

Is CellCept same as tacrolimus?

Prograf (tacrolimus) is a good medicine that prevents rejection of an organ transplant, but you will need to be on it lifelong. CellCept (mycophenolate) is a first-choice medication for preventing organ rejection since it doesn't hurt the kidneys or liver like its alternatives.

Does tacrolimus affect the heart?

In 100 people receiving Tacrolimus, from 4 to 20 may have: Damage to organs (heart, lungs, brain, others) which may cause changes in thinking, confusion, memory loss or shortness of breath.

What can you not take with tacrolimus?

Avoid grapefruit juice while taking Tacrolimus. Grapefruit and Grapefruit juice increase Tacrolimus blood levels significantly leading to side effects like abdominal pain, confusion, decreased urination, dizziness, headache, mood changes, nausea-vomiting, tremor, yellowing of skin or eyes, weakness, or other problems.

How much does a kidney transplant cost with Medicare?

If you have Original Medicare, you'll pay 20% of the Medicare- approved amount for all covered dialysis related services. Medicare will pay the remaining 80%. If you need a kidney transplant, Medicare will pay the full cost of care for your kidney donor. You pay nothing for Medicare-approved laboratory tests.

How much does a kidney transplant cost?

Kidney Transplantation Costs

In 2020, the average kidney transplant cost was US$442,500 (6). Charges for the transplant admission, which include the surgery itself, are the most expensive line item, accounting for 34% of the total cost.

Does Medicare Part D cover transplant drugs?

Medicare may cover transplant surgery as a hospital inpatient service under Part A. Medicare covers immunosuppressive drugs if the transplant was covered by Medicare or an employer or union group health plan was required to pay before Medicare paid for the transplant.

Does tacrolimus affect sleep?

Conclusion: In our population, insomnia is common after lung transplantation, with prevalence greater than the general population. Higher cumulative exposure to tacrolimus may contribute to insomnia in this group.

What foods affect tacrolimus levels?

Avoid excessive intake of high potassium foods (bananas, oranges, orange juice, potatoes, spinach, etc). Do not eat grapefruits, grapefruit juice or any soda (Fresca) or fruit juice blend that contains grapefruit juice. Grapefruit can increase your levels of tacrolimus to a potentially toxic level.

Who should not take tacrolimus?

You should not use this medicine if you are allergic to tacrolimus or hydrogenated castor oil, or if you have used cyclosporine (Neoral, Sandimmune, Gengraf) within the past 24 hours. Using tacrolimus may increase your risk of developing serious infections or certain types of cancer, such as lymphoma or skin cancer.