What tier of drug is Prolia?

Asked by: Bernadine Goldner III  |  Last update: November 11, 2025
Score: 5/5 (45 votes)

What drug tier is Prolia typically on? Medicare prescription drug plans typically list Prolia on Tier 4 of their formulary.

How much does a Prolia shot cost without insurance?

How much does Prolia cost without insurance? If you do not have health insurance coverage, then your out-of-pocket costs for Prolia may be as high as $2,201.2 for 1, 1ML of 60MG/ML Syringe. Save on this total by using a SingleCare Prolia coupon.

What is the downside to Prolia?

Common Prolia (denosumab) side effects include aches and pains in your muscles and bones. These are typically mild and can be managed at home. Rare but serious Prolia side effects include low blood calcium levels, thigh bone fractures (breaks), and osteonecrosis of the jaw.

What is the classification for Prolia?

Denosumab is a RANK ligand (RANKL) inhibitor used for the management of osteoporosis in patients at high risk for bone fractures.

Is Prolia a Tier 3 drug?

Medicare prescription drug plans typically list Prolia on Tier 4 of their formulary.

Can You Stop Prolia? Or Will It INCREASE Fracture Risk??

31 related questions found

What are the three worst bone density drugs?

A variety of medications can increase bone loss and/or fall risk:
  • Synthetic Glucocorticoids (e.g. Prednisone) ...
  • Breast Cancer Drugs. ...
  • Prostate Cancer Drugs. ...
  • “Heartburn” Drugs. ...
  • Depo-Provera. ...
  • Excessive Thyroid Hormone Replacement. ...
  • Anti-seizure and Mood-altering Drugs. ...
  • Blood Pressure Medication.

Why do doctors push Prolia?

It helps stop the development of bone-removing cells before they can reach and damage the bone. Prolia® works by targeting a molecule that the bone-removing cells need in order to work. Prolia® helps stop the development of bone-removing cells before they can reach and damage the bone.

What is the safest osteoporosis drug to take?

Teriparatide and abaloparatide are safe and generally well-tolerated medications.

What is the new alternative to Prolia?

FDA approved Jubbonti (denosumab-bbdz) injection as an interchangeable biosimilar to U.S.-licensed Prolia (denosumab), and Wyost (denosumab-bbdz) injection as an interchangeable biosimilar to U.S.-licensed Xgeva (denosumab).

What do dentists say about Prolia?

Recent studies indicate an association between Prolia use and an increased risk of complications, including osteonecrosis of the jaw, following dental procedures.

What drugs should not be taken with Prolia?

Common medications that may interact with Prolia include:
  • calcimimetic agents such as cinacalcet.
  • chemotherapy agents, such as cyclophosphamide, methotrexate, or bleomycin.
  • corticosteroids (such as prednisone or dexamethasone)
  • immunosuppressants (such as azathioprine, cyclosporine, or tacrolimus).

How can I get my Prolia shot for free?

Amgen Safety Net Foundation (ASNF) is a nonprofit patient assistance program sponsored by Amgen that provides Prolia ® at no cost to qualifying patients who have a financial need and who are uninsured or have insurance that excludes Prolia ®.

Can I stop Prolia after one injection?

Even if you stop using Prolia after just one shot, or you skip one dose of Prolia, your risk of fracture may be increased. This includes the risk of spinal fractures. And if you've already had a fracture in your spine, your risk of having more than one broken bone in your spine is also increased.

How to pay less for Prolia?

Helping eligible commercially insured patients lower out-of-pocket costs
  1. For Prolia®, pay as little as $25 out-of-pocket for each dose.
  2. Can be applied to deductible, co-insurance, and co-payment*

Are injectable drugs covered by Medicare Part B?

Injectable and infused drugs: Medicare covers most injectable and infused drugs when a licensed medical provider gives them. Oral End-Stage Renal Disease (ESRD) drugs: Medicare covers some oral ESRD drugs if the same drug comes in an injectable form and the Part B ESRD benefit covers it.

What is the best drink for bone density?

To help prevent osteoporosis, instead sip these drinks:
  • 8 ounces of orange juice fortified with calcium and vitamin D.
  • A mixture of fortified orange juice and seltzer or club soda that's free of phosphoric acid.

Can I live to 90 with osteoporosis?

Does osteoporosis affect life expectancy? Osteoporosis is not a terminal illness and does not directly influence life expectancy. However, having a fracture can affect it. For example, a 2021 study found that older adults living in a care facility who experienced a hip fracture had a 25% death rate after 3 months.

What is the new drug for osteoporosis in 2024?

Abaloparatide is an anabolic drug and works in a slightly different way to many other drug treatments by stimulating bone formation. This new alternative has the potential to change thousands of lives by keeping people safe from life-changing spinal fractures and broken hips.

What is the controversy with Prolia?

Denosumab (Prolia) goes even further in interfering with immune factors to prevent the natural process of bone breakdown and renewal: A full 6% of those who use Prolia will develop a spontaneous vertebral fracture after stopping the drug, unless they're put immediately on a strong bone drug like Reclast to halt bone ...

Which fruit is best for bones?

Figs contain minerals and vitamins that are essential for bone health. One cup of stewed figs has about 180 milligrams of calcium, plus some vitamins C and vitamin K. Raw figs are low in calories and high in fiber, so they're good for your diet—a couple of raw figs can give you about 24 milligrams of calcium.

Is weight gain a side effect of Prolia?

No, weight gain wasn't reported as a side effect of Prolia in clinical trials. But weight gain may be a symptom of a side effect called peripheral edema. With peripheral edema, fluid builds up in your body and causes swelling in your arms and lower legs.

Which is safer, Fosamax or Prolia?

And when comparing Prolia versus Fosamax, Prolia may be preferred for people who are at very high risk for fracture. The most common side effects of Boniva and Fosamax are gastrointestinal symptoms like indigestion, nausea, and diarrhea.

What is the gold standard treatment for osteoporosis?

Bisphosphonates are often the first choice for osteoporosis treatment. These include: Alendronate (Fosamax), a weekly pill. Risedronate (Actonel, Atelvia), a weekly or monthly pill.

Are bananas good for osteoporosis?

Are bananas bad for osteoporosis? There is no proven link between bananas and worsened osteoporosis symptoms. In fact, bananas, rich in potassium, may benefit bone health by helping to conserve calcium, crucial for strong bones.