Which Shingrix shot has more side effects?
Asked by: Miss Berneice Mayer | Last update: December 3, 2025Score: 4.7/5 (63 votes)
Are the side effects of the second Shingrix shot worse than the first?
In many cases, you may experience similar side effects from both your first and second shot. However, in clinical trials , after receiving the second dose of Shingrix, headache and shivering were reported more often. So after your second dose of Shingrix, you may be at a higher risk of these side effects occurring.
What are the side effects of the Shingrix vaccine for seniors?
- Pain, redness, and swelling at the injection site.
- Muscle pain.
- Tiredness.
- Headache.
- Shivering.
- Fever.
- Upset stomach.
How to lessen Shingrix side effects?
Taking an over-the-counter pain medicine such as ibuprofen or acetaminophen after getting Shingrix can help ease discomfort from side effects. Contact your doctor if you have serious side effects.
What percentage of people have a bad reaction to Shingrix?
Adverse events of arthralgia, infective pneumonia, and influenza-like illnesses occurred in ≥1% of recipients of SHINGRIX and at a rate at least 1.5-fold higher than placebo (1.5% vs 1.0%, 1.5% vs 0.9%, and 1.3% vs 0.6%, respectively).
What are the side effects of the shingles shot?
When do Shingrix side effects peak?
Side effects typically occur a few hours after receiving the second shot. These symptoms typically last one to three days. If symptoms last longer than one week, talk to your doctor.
How common is Guillain-Barré after the Shingrix vaccine?
The study found an increased risk of GBS (estimated 3 excess cases per million doses administered) observed in the 42 days following vaccination. The PI noted that the evidence was insufficient to determine a causal relationship.
What is the controversy with the Shingrix vaccine?
Some people who have, or will have, a weakened immune system may receive the second dose 1 to 2 months after the first dose. In 2021, the FDA issued a black box warning for Shingrix regarding the potential increased risk of Guillain–Barré syndrome (GBS) following Shingrix vaccination.
What medications to avoid after shingles vaccine?
- acetaminophen.
- anakinra.
- azathioprine.
- baricitinib.
- cancer medications (e.g., carboplatin, cyclophosphamide, doxorubicin, ifosfamide, venetoclax, vincristine)
Who should not have the Shingrix vaccine?
However, you should not give Shingrix to patients who are experiencing an acute episode of herpes zoster.
Does Tylenol reduce the effectiveness of Shingrix?
No interactions were found between acetaminophen and Shingrix.
Is there a downside to the shingles vaccine?
The most common side effects of a shingles vaccine are headaches and pain, soreness, swelling and itching where the shot was given. On white skin, the area might look red. On Black or brown skin the redness might be harder to see.
Do I really need the 2nd shingles shot?
1 The second dose is given between 2 and 6 months after the first. Don't skip the second shot, even if you are concerned about side effects. If you don't get the second Shingrix shot, you'll be less protected from shingles than you will be if you get both shots.
Should you rest after the shingles vaccine?
Plan to take it easy after your shingles vaccine. Get plenty of rest, and you should notice your energy levels start to improve within a few days.
Is it normal to be extremely tired after getting the shingles shot?
Side effects of the shingles vaccine
swelling, itchiness, bruising or pain where the injection was given. a headache. an aching body. feeling tired.
How can I reduce the side effects of Shingrix?
Taking an over-the-counter pain medicine such as ibuprofen or acetaminophen after getting Shingrix can help ease discomfort from side effects. Contact your doctor if you have serious side effects.
When do Shingrix side effects start?
Typically, Shingrix side effects start within days or even hours within receiving the vaccination, and they can resolve on their own within two to five days. Commonly reported side effects of the Shingrix second dose include pain, fever, and swelling.
Why was the shingles vaccine taken off the market?
Merck & Co.'s Zostavax was discontinued in 2020 because of waning effectiveness over time. Curevo hopes to change that and go head-to-head with GSK's Shingrix — which notched $4.3 billion sales last year — with a vaccine that's as effective but has a lower rate of side effects.
Why is the shingles vaccine not given over 80?
The vaccine's effect diminishes with age, therefore people aged 80 or older aren't eligible to receive the vaccine.
What triggers shingles to flare up?
After having chickenpox, the virus stays in the nerve cells of your body but is not active. Shingles occurs when the virus becomes active again usually many years later. The virus may be reactivated by stress, illness, immunosuppression, older age, trauma and radiotherapy. But shingles often occurs for no known reason.
Why do some doctors not recommend the shingles vaccine?
But safety in pregnant women has not been proven yet, and so it is not recommended during pregnancy. Severe reaction to an earlier dose. If you had a severe allergic reaction after the first dose of RZV, you shouldn't have the second dose. Be careful also if you have had allergic reactions to other vaccines.
Why was Shingrix recalled?
The recall is a precautionary measure due to the potential for loss of integrity of the antigen vial, although a search of GSK's global adverse event database has not identified a safety signal for Shingrix lot #9LH3Y related to infections or lack of efficacy, events that could occur if there were a loss of integrity ...
How long after vaccination can you get Guillain Barre Syndrome?
Findings. In this cohort study of surveillance data from the Vaccine Safety Datalink that included 15.1 million doses of COVID-19 vaccines, the unadjusted incidence rate of confirmed GBS in the 1 to 21 days after receiving the Ad. 26. COV2.