Who should not take naproxen?

Asked by: Janiya Konopelski PhD  |  Last update: November 13, 2025
Score: 4.1/5 (26 votes)

have ever had an allergic reaction to aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen. have or have had stomach ulcers, bleeding in the stomach or intestines, or a hole in your stomach. have high blood pressure. have severe liver or kidney failure.

What drugs cannot be taken with naproxen?

Cautions with other medicines
  • other anti-inflammatory medicines, such as aspirin or ibuprofen.
  • medicines that help to prevent blood clots, such as warfarin or rivaroxaban.
  • steroids, such as prednisolone.
  • medicines that make you pee more (diuretics), such as furosemide.

What organ is naproxen bad for?

Naproxen can cause an ulcer in your stomach or gut if you take it for a long time or in big doses, or if you're older or in poor general health. Your doctor may tell you not to take naproxen if you have a stomach ulcer or you have had one in the past.

Can I take naproxen if I have high blood pressure?

In general, people with high blood pressure should use acetaminophen or possibly aspirin for over-the-counter pain relief. Unless your health care provider has said it's OK, you should not use ibuprofen, ketoprofen, or naproxen sodium.

Why should you avoid coffee when taking naproxen?

But combining naproxen and coffee can increase the risk of stomach inflammation (gastritis). In studies, people who drank coffee had an increased risk of developing stomach irritation. This may have to do with the effects of caffeine, the acidic nature of coffee, or both.

Taking NSAIDs Safely

23 related questions found

Why should you not lay down for 10 minutes after taking naproxen?

Do not lie down for at least 10 minutes after taking this drug to prevent irritation inside your throat (esophagus). If this medication upsets your stomach, you may take it with food, milk, or an antacid. Do not take this medication unless you have time for a full night's sleep of at least 7 to 8 hours.

What not to drink with naproxen?

Naproxen is also an NSAID, existing within a group of drugs that can interfere with the hormones needed to protect the stomach lining. For this reason, drinking alcohol and taking naproxen at the same time can put individuals at a heightened risk of gastritis.

What are two blood pressure medications to avoid?

5 of the worst blood pressure medications
  • Beta blockers. Usually, beta blockers aren't used as first-choice therapies to lower blood pressure. ...
  • Loop diuretics. Furosemide (Lasix) is a type of diuretic (water pill) known as a loop diuretic. ...
  • Alpha blockers. ...
  • Vasodilators. ...
  • Alpha-2 agonists.

What is the main side effect of naproxen?

Feeling sleepy is a common side effect of naproxen. You may you feel drowsy, tired or dizzy. Avoid driving, using machinery or doing other tasks that require concentration until you know how this medication affects you. Talk to your healthcare provider if you're concerned about sleepiness or other side effects.

What is the safest pain reliever to take?

Acetaminophen is generally considered safer than other pain relievers. It doesn't cause side effects such as stomach pain and bleeding.

Does naproxen make you pee a lot?

Bladder problems: This medication may cause bladder pain, painful or difficult urination, or increased frequency of urination. If these symptoms occur without an explanation (e.g., infection), stop taking this medication and contact your doctor.

What is the problem with naproxen?

Do not take other medications that contain aspirin, ibuprofen, or naproxen with this medication. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur.

Can you stop taking naproxen suddenly?

If you regularly take naproxen, you should not suddenly stop without speaking to a doctor. This may lead to withdrawal symptoms and can also increase your risk of developing clots. If you regularly take naproxen and wish to stop, speak to your doctor about gradually lowering your dose.

What supplements to avoid with naproxen?

Naproxen has caused kidney problems and increased blood potassium levels, especially in older people. People taking naproxen should not supplement potassium without consulting with their doctor.

What happens if I accidentally take 2 naproxen 500 mg?

An overdose of naproxen can cause nausea, vomiting, abdominal pain, and sometimes drowsiness, ataxia (i.e., wobbly walking), ringing in the ears, and disorientation.

What is the disadvantage of naproxen?

Naproxen can cause an ulcer in your stomach or gut if you take it for a long time. Your doctor may tell you not to take naproxen if you have a stomach ulcer or you have had one in the past.

How to settle the stomach after naproxen?

You should take Omeprazole before food and taking Naproxen. Taking Omeprazole before will ensure that it is fully absorbed by the body and can offer adequate protection for the stomach lining when Naproxen is taken and starts to be digested and absorbed by the stomach.

What is the strongest anti-inflammatory medication?

Naproxen is considered to be the strongest anti-inflammatory medication available over the counter, says Walia. However, this doesn't mean other OTC anti-inflammatories aren't just as effective at reducing inflammation — they just have different durations of action.

What is the number one fruit to lower blood pressure?

Fruits that can help lower blood pressure in the long term include strawberries, blueberries, bananas, watermelon, and kiwis . Drinking pomegranate juice may also help .

What should I do if my BP is 140-90?

If you have a BP of 140/90, that is considered high blood pressure and you should discuss this with your doctor. The first thing that is usually recommended for people with high blood pressure to do is lifestyle changes such as: Maintaining a healthy weight. Consuming a healthy balanced diet low in salt.

Can I drink coffee while taking naproxen?

This medication may irritate the stomach, and should be taken with food. It is best to avoid coffee, spicy food or alcohol.

How do I protect my stomach with naproxen?

If you're taking naproxen for a long time or at risk of getting a stomach ulcer, your doctor may prescribe a medicine, such as omeprazole or lansoprazole, to protect your stomach.

Should you drink a lot of water with naproxen?

Should I take Aleve with food or liquid? A full glass of water is required. Take with food or milk if an upset stomach occurs.