Is there anything better than Ozempic for weight loss?

Asked by: Stanley Volkman PhD  |  Last update: September 29, 2025
Score: 4.4/5 (67 votes)

Ozempic acts like a hormone your body makes. Mounjaro works similarly, but it acts like two hormones instead of one. Compared to Ozempic, Mounjaro might work even better for weight loss. One study showed that a 15 milligram-dose of this drug taken every week led people to lose more than 20% of their body weight.

What weight loss drug is replacing Ozempic?

Wegovy (semaglutide) Wegovy is the same medication as Ozempic and was FDA-approved for chronic weight management in 2021. It's even sometimes referred to as “the new Ozempic.” For dosing, you'll start off on a 0.25mg injection per week, then your doctor may increase every month until you reach 1.7mg or 2.4mg per week.

What is the new drug that is better than Ozempic?

Mounjaro is considered more effective than Ozempic and Wegovy because it acts on GLP-1 receptors as well as the receptors of another hormone called GIP.

Why is Mounjaro better than Ozempic?

By hitting both these receptors, Mounjaro is essentially double-teaming your appetite and blood sugar. Because it's working on two fronts, Mounjaro is generally prescribed in higher doses than Ozempic. You usually start at 2.5 mg and can go all the way up to 15 mg.

Is zepbound better than Mounjaro for weight loss?

Zepbound and Mounjaro are basically the same drug, but they're approved for different medical conditions: Zepbound for weight loss and Mounjaro for diabetes. Similarly, Wegovy and Ozempic are the same drug, but with different names and different doses for different conditions.

Mounjaro is more effective than Ozempic for weight loss, study finds

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How much weight can you lose on Mounjaro in 3 months?

Weight loss doesn't happen overnight, and it could take up to 18 months to get the results you're looking for from Mounjaro. You can expect to lose 6% of your body weight after two months, 9% after three months, and 11% after four months. But by the 18-month mark, Mounjaro patients experience around 21% weight loss.

How did Kelly Clarkson lose weight?

Kelly Clarkson's weight loss was motivated by health concerns, including autoimmune and thyroid conditions. She combined diet changes, such as adopting a lectin-free diet, with regular exercise like walking. Clarkson's journey included using weight loss medication, although she emphasized a holistic approach.

Do you gain weight back after stopping Mounjaro?

Weight gain is common when you stop GLP-1 weight loss medications like Mounjaro, and studies show people can put up to 14% of their weight back on. When you stop Mounjaro, its beneficial effects stop too. Some people notice an increase in their appetite and may revert back to their previous diet.

Is Wegovy better than Ozempic?

It depends on factors like your health history, medical needs, and treatment goals. While Ozempic is the preferred option for blood sugar control and cardiovascular risk in adults with diabetes, Wegovy may be a better option for people living with obesity. Talk with your healthcare provider about both options.

How much does Mounjaro cost per month?

Mounjaro (tirzepatide) is a prescription medication that's FDA approved to treat Type 2 diabetes. Without insurance, the average monthly cost of Mounjaro is between $1,000 to $1,200, depending on the pharmacy.

What is the poor man's Ozempic supplement?

Due to the similar effect, psyllium husk is now often known as the 'the poor man's Ozempic' by many people online, including Dr Enaka Yembe. She said: “Although psyllium husk and Ozempic are very different substances, they have similar effects. “They both induce feelings of fullness.

Can you really get Wegovy for $25?

Yes, you can really get Wegovy for $25 if you meet certain criteria. Offered by Novo Nordisk, the Wegovy Savings Card awards qualified individuals the opportunity to get the medication for $25 per month (i.e. 28-day supply).

What is the strongest weight loss prescription pill?

Some of the strongest weight loss pills available today include: Naltrexone/bupropion (brand name Contrave) Phentermine/topiramate (brand name Qsymia) Orlistat (brand names Xenical, Alli)

Why is Zepbound better than Ozempic?

Zepbound and Ozempic have different dosages, and the gradual increase to the maintenance (highest) dose is faster with Zepbound. Studies indicate that Zepbound may help people lose more weight. (Note: It's important to remember that the goal isn't maximum weight loss but reaching your optimal weight.)

What is the best substitute for Ozempic?

Due to an increased demand, Ozempic may be difficult for some people to find. For Type 2 diabetes, Rybelsus (semaglutide) is an oral Ozempic alternative that contains the same active ingredient. Trulicity (dulaglutide) and Mounjaro (tirzepatide) are also once-weekly injections that work in a similar way.

Which is better, Mounjaro or Ozempic for weight loss?

In a recent study published in JAMA Internal Medicine, researchers compared Ozempic and Mounjaro in real-world conditions and found that people who took Mounjaro lost significantly more weight than those who took Ozempic. Moreover, the longer the patients kept taking the drugs, the wider the gap became.

How did Melissa McCarthy lose weight?

Melissa told People magazine that after she landed her role on Gilmore Girls, she attempted a doctor-supervised all-liquid diet, which led her to lose 70 pounds in four months.

How did Adele lose weight?

Adele's routine involved daily workouts, including weight training and cardio. She worked with a trainer to create a balanced plan that fit her lifestyle. This consistent exercise helped her build strength and boost her fitness level.

Did Christina Aguilera use Ozempic to lose weight?

She admitted that prior to taking Ozempic, she did attempt to lose the weight naturally through diet and exercise.

Can I realistically lose 20 pounds in 3 months?

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Losing 20 pounds in three months is an ideal goal. That means losing a little more than 1.5 pounds per week. According to the CDC, losing 1 to 2 pounds a week gives you the best weight-loss results in the long-term.

What is the best injection for weight loss?

The top prescription weight loss injections include Wegovy, Zepbound, Saxenda, Mounjaro, and Ozempic. Each of these medications has unique benefits and considerations: Wegovy (Semaglutide): Approved by the FDA in 2021, Wegovy is known for helping users lose about 15% of their body weight over 68 weeks.

Can you lose 20 pounds in a month on Mounjaro?

According to data from randomised controlled trials, Mounjaro supports weight loss of around 4% of body weight after one month. After two months, it's around 6% of body weight.