When did Prograf go generic?
Asked by: Otis Emmerich | Last update: January 10, 2026Score: 4.4/5 (69 votes)
What is the difference between Prograf and tacrolimus?
Tacrolimus oral capsules are drugs approved by FDA for prevention of organ rejection in adult and pediatric patients who received certain types of organ transplants. Prograf is the brand name for tacrolimus oral capsules.
How much does Prograf cost without insurance?
How much does Prograf cost without insurance? Without the necessary insurance coverage, you may end up paying as much as $552.06 for 60, 1MG Capsule of Prograf. To save on this cost, use a SingleCare Prograf coupon and pay only $24.17 for 60, 1mg Capsule of generic Prograf.
Is there a difference between brand and generic tacrolimus?
These data indicate that the generic tacrolimus preparation is bioequivalent to reference tacrolimus in kidney transplant recipients according to the FDA guidelines. The findings will also apply to the branded generic tacrolimus Hecoria™, which has an identical formulation to the Sandoz generic.
Is there a generic for Prograf?
Tacrolimus (Prograf) is a medication used to prevent organ rejection after an organ transplant. The immediate-release (IR) capsules are available as a lower-cost generic medication, whereas the IR granules (Prograf) and extended-release (ER) capsules (Astagraf XL) are only available as brand-name medications.
Dr Reddy's Drugs Could KILL You | Generic Tacrolimus
What is the substitute for Prograf?
Nulojix® is an injectable medication that works in a different way than any other anti-rejection medicines available. It was designed as a potential replacement medication for Prograf® (tacrolimus) or Neoral® (Gengraf®, cyclosporine).
Why is Prograf hazardous?
Hazard Statements (GHS-US) : May form combustible dust concentrations in air. H361 - Suspected of damaging fertility or the unborn child. H372 - Causes damage to organs (immune system, kidneys) through prolonged or repeated exposure.
Can you switch brands of tacrolimus?
Switching between brands of tacrolimus requires careful therapeutic monitoring under the supervision of a transplant specialist.
Which company tacrolimus is best?
- Glenmark Pharmaceuticals Limited-
- Contiderma-
- Healing Pharma India Pvt Ltd- Connote Healthcare- Lexine Technochem Private Limited- Astonea Labs Limited- Concord Biotech Limited- Biocon- Prevego Healthcare & Research Private Limited- Torrent Pharma- Conclusion-
Is there a shortage of tacrolimus?
Why does my tacrolimus look different? Your tacrolimus looks different because we are getting the capsules from different manufacturers. This is because of a severe, nationwide shortage of the ingredients needed to make tacrolimus capsules.
Does Medicare pay for tacrolimus?
What drug tier is tacrolimus typically on? Medicare prescription drug plans typically list tacrolimus on Tier 2 of their formulary. Generally, the higher the tier, the more you have to pay for the medication. Most plans have 5 tiers.
What does Prograf do to your body?
Tacrolimus (Astagraf XL, Envarsus XR, Prograf) is used along with other medications to prevent rejection (attack of a transplanted organ by the immune system of a person receiving the organ) in people who have received a kidney transplant.
What is the problem with tacrolimus?
This medicine may cause serious brain or nerve problems (eg, posterior reversible encephalopathy syndrome). Tell your doctor right away if you have blurred vision, confusion, dizziness, headache, mental changes, seizures, high blood pressure, unusual drowsiness, tiredness, or weakness, or a fast heartbeat.
Does Prograf cause hair loss?
Hair loss has been observed in patients taking Tacrolimus after organ transplant, particularly in middle-aged females who have been taking the drug for 5 – 10 years.
Does magnesium affect tacrolimus levels?
Serum magnesium levels correlated inversely with tacrolimus concentrations and creatinine clearance. Conclusion: Hypomagnesemia in renal transplant recipients results from renal magnesium wasting. Tacrolimus levels and renal function impact on the excess renal magnesium excretion.
What is the Prograf Copay Assistance Program?
The Prograf Patient Assistance Program is designed to assist patients who have no health insurance and limited financial resources. To be eligible for the program, patients must meet income, residency and insurance criteria.
Is tacrolimus safer than steroid?
McNeill and Koo stated that animal and human studies suggest that topical tacrolimus is a safe alternative to topical steroids, with only transient burning sensation as the major known adverse effect compared with those of topical steroids, including long-term side effects.
What is the normal range of tacrolimus level?
Most individuals display optimal response to tacrolimus with trough whole blood levels of 5.0 to 15.0 ng/mL. Preferred therapeutic ranges may vary by transplant type, protocol, and comedications. Therapeutic ranges are based on specimen collected at trough (ie, immediately before a scheduled dose).
What not to eat with tacrolimus?
Does tacrolimus interact with any foods or beverages? Avoid excessive intake of high potassium foods (bananas, oranges, orange juice, potatoes, spinach, etc). Do not eat grapefruits, grapefruit juice or any soda (Fresca) or fruit juice blend that contains grapefruit juice.
What can be used instead of Prograf?
Does tacrolimus raise creatinine levels?
On the other hand, high doses of tacrolimus significantly increased serum creatinine levels when compared with the control group and the SHAM group but lower doses did not cause significant changes.
What cancers does tacrolimus cause?
A small number of patients who used tacrolimus ointment or another similar medication developed skin cancer or lymphoma (cancer in a part of the immune system).
What medications cannot be taken with tacrolimus?
Strong interactions have been observed with antifungal agents such as ketoconazole, fluconazole, itraconazole and voriconazole, the macrolide antibiotic erythromycin or HIV protease inhibitors (e.g. ritonavir). Concomitant use of these substances may require decreased tacrolimus doses in nearly all patients.
Does Prograf raise blood sugar?
This medicine may increase blood sugar. Ask your health care provider if changes in diet or medicines are needed if you have diabetes. Avoid taking medicines that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your health care provider. These medicines may hide a fever.